Risk Management for Dual-Use Potential

Publication of the Risk Management for Dual-Use Potential in Life Science Research Guideline

The Public Health Agency of Canada, in collaboration with the Canadian Food Inspection Agency, is pleased to announce the publication of the Risk Management for Dual-Use Potential in Life Science Research guideline, on March 31, 2026.

The Dual-Use Guideline provides comprehensive guidance on how to identify, assess, and mitigate the risks associated with the dual-use potential of research involving pathogens, toxins, or other biological material.

The Dual-Use Guideline was developed in response to a growing international concern regarding dual-use potential in life science research and highlights a need to balance the advancements of scientific research with protecting the community and the environment from harm. It also touches on the biosafety and biosecurity risks associated with emerging technologies, such as artificial intelligence, as well as international initiatives that aim to mitigate risks associated with dual-use potential.

The DualUse Guideline highlights that a Plan for Administrative Oversight for pathogens and toxins in a research setting is a key component of an effective risk management program. Before a licence can be issued, organizations intending to conduct scientific research (as defined in the Human Pathogens and Toxins Regulations) must have a Plan for Administrative Oversight [Human Pathogens and Toxins Regulations 3].

For questions about the Dual-Use Guideline, please email pathogens.pathogenes@phac-aspc.gc.ca.